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Prion Protein Monoclonal Antibody - BAR 233
Antibodies - Monoclonal Antibodies

Size: 200 µg
서한형 대리
010-8832-6303

제품소개

Territorial Availability: Available worldwide directly through Bertin or your local distributor
Synonyms:
  • Prion Protein Monoclonal Antibody - BAR 233
Correlated keywords:
  • proteins
  • mad
  • cow
  • diseases
  • bovine
  • spongiform
  • encephalopathy
  • scrapie
  • Creutzfeldt-jakob
  • neurodegeneration
  • antibodies
  • antisera
  • antiserum
  • neurochemistry
  • neuroscience
  • spi-bio
  • spibio
  • A03200
Product Overview:
Prion Protein (PrP) and namely its abnormal isoform, partially resistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathie (BSE) or its human form, the New Variant of Creutzfeld-Jakob disease.
This antibody recognises the protein sequence within amino acids 141-152 (human numbering).
Size200 µg
ShippingDry Ice
HostMouse
AntigenThis anti-Prion Protein Monoclonal Antibody was raised against an ovine recombinant protein.
CloneBAR233
IsotypeIgG2b
Application(s)

Reconstitute the content of the vial in 1 mL of water.

For western blot analysis of PrPc, dilute to a final concentration of 1 µg/mL and use BSA as blocking reagent. For EIA and flow cytometry, the optimal working must be determined empirically (currently between 0.1 and 1 µg/mL).

Specificity
Application MediaReconstitute the content of the vial in 1 mL of water.
Formulationlyophilized IgG with BSA
Custom Code3822000000
UNSPSC code12352203

Féraudet C., et al. Screening of 145 Anti-PrP Monoclonal Antibodies for Their Capacity to Inhibit PrPSc Replication in Infected Cells. The journal of Biological Chemistry. Vol. 280. No. 12, March 25, pp. 11247-11258, 2005.

Selective and Efficient Immunoprecipitation of the Disease-associated Form of the Prion Protein Can Be Mediated by Nonspecific Interactions between Monoclonal Antibodies and Scrapie-associated Fibrils.The journal of Biological Chemistry. Vol. 279. No. 29, July 16, pp. 30143-30149, 2004.

주문정보

CAT.No 품명 규격 비고
A03223 Prion Protein Monoclonal Antibody - BAR 233 200 µg Antibodies - Monoclonal Antibodies