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Prion Protein Monoclonal Antibody - 12F10
Antibodies - Monoclonal Antibodies

Size: 200 µg
서한형 대리
010-8832-6303

제품소개

Territorial Availability: Available worldwide directly through Bertin or your local distributor
Synonyms:
  • Prion Protein Monoclonal Antibody - 12F10
Correlated keywords:
  • proteins
  • mad
  • cow
  • diseases
  • bovine
  • spongiform
  • encephalopathy
  • scrapie
  • Creutzfeldt-jakob
  • neurodegeneration
  • antibodies
  • antisera
  • antiserum
  • neurochemistry
  • neuroscience
  • spi-bio
  • spibio
  • A03200
Product Overview:
Prion Protein (PrP) and namely its abnormal isoform, partially resistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathie (BSE) or its human form, the New Variant of Creutzfeld-Jakob disease.
This antibody recognises the protein sequence within amino acids 142-160 (human numbering).
Size200 µg
ShippingDry Ice
HostMouse
AntigenThis anti-Prion Protein Monoclonal Antibody was raised against a human recombinant protein.
Clone12F10
IsotypeIgG2a
Application(s)

Reconstitute the content of the vial in 1 mL of water.

For immunohistochemistry, the optimal working dilution must be determined empirically (currently between 0.1 and 1 µg/mL). For western blot analysis of PrPc, dilute the antibody to a final concentration of 1 µg/mL.

Specificity
Application MediaReconstitute the content of the vial in 1 mL of water.
Formulationlyophilized IgG with BSA
Custom Code3822000000
UNSPSC code12352203

Krasemann S. et al. Generation of monoclonal antibodies against prion proteins with an unconventional nucleic acid-based immunization strategy. Journal of Biotechnology 73, 119-129 (1999).

Krasemann S. et al. Induction of antibodies against human prion proteins (PrP) by DNA-mediated immunization of PrP 0/0 mice. Journal of Immunological Methods 199, 109-118 (1996).

Krasemann S. et al. Generation of monoclonal antibody against Human prion proteins in PrP 0/0 Mice.

Molecular Medecine, 2, 725-731 (1996).

주문정보

CAT.No 품명 규격 비고
A03221 Prion Protein Monoclonal Antibody - 12F10 200 µg Antibodies - Monoclonal Antibodies