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Prion Protein Monoclonal Antibody - SAF 70
Antibodies - Monoclonal Antibodies

Size: 200 µg
서한형 대리
010-8832-6303

제품소개



Territorial Availability: Available worldwide directly through Bertin or your local distributor
Synonyms:
  • Prion Protein Monoclonal Antibody - SAF 70
Correlated keywords:
  • proteins
  • mad
  • cow
  • diseases
  • bovine
  • spongiform
  • encephalopathy
  • scrapie
  • Creutzfeldt-jakob
  • neurodegeneration
  • antibodies
  • antisera
  • antiserum
  • neurochemistry
  • neuroscience
  • spi-bio
  • spibio
  • A03200
Product Overview:
Prion Protein (PrP) and namely its abnormal isoform, partially resistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathie (BSE) or its human form, the New Variant of Creutzfeld-Jakob disease.
This antibody recognises the protein sequence within amino acids 142-160 (human numbering).
Size200 µg
ShippingDry Ice
HostMouse
AntigenThis anti-Prion Protein Monoclonal Antibody was raised against a preparation of SAF (scrapie associated fibrils) from infected hamster brain.
CloneSAF 70
IsotypeIgG2b
Application(s)

Reconstitute the content of the vial in 1 mL of water.

For western blot analysis of PrPc, dilute the antibody to a final concentration of 1 µg/mL.

Specificity
Application MediaReconstitute the content of the vial in 1 mL of water.
Formulationlyophilized IgG with BSA
Custom Code3822000000
UNSPSC code12352203

Nishida N., et al. Successful Transmission of Three Mouse-Adapted Scrapie Strains to Murine Neuroblastoma Cell Lines Overrexpressing Wild-Type Mouse Prion Protein. Journal of Virology 320-325 (January 2000).

Vincent B., et al. Phorbol Ester-regulated Cleavage of Normal Prion Protein in HEK293 Human Cells and Murine Neurons. The journal of Biological Chemistry. Vol. 275, No 45, Issue of November 10, pp.35612-35616 (2000).

Demart S., et al. New Insight into Abnormal Prion Protein Using Monoclonal Antibodies.Biochemical and Biophysical Research Communications 265, 652-657 (1999).

주문정보

CAT.No 품명 규격 비고
A03206 Prion Protein Monoclonal Antibody - SAF 70 200 µg Antibodies - Monoclonal Antibodies