Territorial Availability: Available worldwide directly through Bertin Bioreagent or your local distributor
Technical Warning: Check the Additional Items Required section of this kit booklet to verify if UltraPure Water (Milli-Q or equivalent) is needed for this assay
Product Overview:
Adiponectin, also referred to as Acrp30, AdipoQ and GBP-28, is an 244 aminoacid protein, which is physiologically active, specifically and highly expressed in adipose cells (adipokine). Adiponectin forms homotrimers, which are the building blocks for higher order complexes found circulating in serum. Paradoxically, adipose tissue-expressed adiponectin levels are inversely related to the degree of adiposity. A reduction in adiponectin serum levels is accompanied by insulin resistance states, such as obesity and type II diabetes mellitus. Adiponectin has been shown to increase insulin sensitivity and decrease plasma glucose by increasing tissue fat oxidation. It inhibits the inflammatory processes of atherosclerosis suppressing the expression of adhesion and cytokine molecules in vascular endothelial cells and macrophages, respectively.
Size: 96 wells
Shipping: Wet ice
Stability: Store at +4degrees; shelf life 6 months maximum after production
Application Media: Human Serum, Plasma, Breast Milk, Urine and Tissue Culture Supernatant|1/300 dilution for serum and plasma, 1/3 for breast milk and urine prior assay
Sample volume: 5 µL
Tracer: HRP
Detection Limit: 0.5 ng/mL
Standard Curve Range: 5-150 ng/mL for serum and plasma
Custom Code: 3822000000
UNSPSC code: 41116104